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S.E.M.I.: Side Effects May Include... key art

S.E.M.I.: Side Effects May Include...

S.E.M.I.: Side Effects May Include... came out for PC on 23 Jan 2026.

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

Developed by
Two Horn Unicorn
Published by
Two Horn Unicorn
Genres
Hack and slash/Beat 'em up, Indie, Arcade
Themes
Action, Comedy, Party

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